KDM5-IN-1 (Standard)
KDM5-IN-1 (Standard) is the analytical standard of KDM5-IN-1 (HY-100422) . This product is intended for research and analytical applications. KDM5-IN-1 is a potent, selective and orally bioavailable KDM5 inhibitor with an IC50 of 15.1 nM.
Product Specifications
CAS Number
[1628210-26-3]
Target
Histone Demethylase; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer
Smiles
N#CC1=C2NC(C3=CN(C(C)(C)C)N=C3)=C(C(C)C)C(N2N=C1)=O
Molecular Formula
C17H20N6O
Molecular Weight
324.38
References & Citations
[1]Liang J, et al. Lead optimization of a pyrazolo[1,5-a]pyrimidin-7 (4H) -one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies. Bioorg Med Chem Lett. 2016 Aug 15;26 (16) :4036-41.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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