BFH772 (Standard)

BFH772 (Standard) is the analytical standard of BFH772 (HY-100419) . This product is intended for research and analytical applications. BFH772 is a potent oral VEGFR2 inhibitor, which is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM[1].

Product Specifications

CAS Number

[890128-81-1]

Target

Reference Standards; VEGFR

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(NC1=CC(C(F)(F)F)=CC=C1)C2=CC=CC3=CC(OC4=NC=NC(CO)=C4)=CC=C32

Molecular Formula

C23H16F3N3O3

Molecular Weight

439.39

References & Citations

[1]Bold G, et al. A Novel Potent Oral Series of VEGFR2 Inhibitors Abrogate Tumor Growth by Inhibiting Angiogenesis. J Med Chem. 2016 Jan 14;59 (1) :132-46.