Soraprazan (Standard)
Soraprazan (Standard) is the analytical standard of Soraprazan. This product is intended for research and analytical applications. Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H, K-ATPase (Ki=6.4 nM), with an IC50 of 0.19 μM in gastric glands. Soraprazan binds to the H, K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H, K-ATPase over Na, K- and Ca-ATPases[1].
Product Specifications
CAS Number
261944-46-1
Target
Proton Pump; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Metabolic Disease
Smiles
O[C@@H]1[C@@H](C2=CC=CC=C2)NC3=C(C=CN4C3=NC(C)=C4C)[C@H]1OCCOC
Molecular Formula
C21H25N3O3
Molecular Weight
367.44
References & Citations
[1]Simon WA, et al. Soraprazan: setting new standards in inhibition of gastric acid secretion. J Pharmacol Exp Ther. 2007 Jun;321 (3) :866-74. Epub 2007 Mar 16.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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