PHCCC (Standard)
PHCCC (Standard) is the analytical standard of PHCCC. This product is intended for research and analytical applications. PHCCC is a Group I mGluR antagonist with an IC50 of 3 μM. PHCCC is a selective positive modulator of mGlu4 receptor. Antiparkinsonian effect[1][2].
Product Specifications
CAS Number
179068-02-1
Target
MGluR; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cancer
Smiles
O=C(C12C(C2)/C(C3=CC=CC=C3O1)=N\O)NC4=CC=CC=C4
Molecular Formula
C17H14N2O3
Molecular Weight
294.31
References & Citations
[1]Marino MJ et al. Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment. Proc Natl Acad Sci U S A. 2003 Nov 11;100 (23) :13668-73.|[2]Récasens M, et al. Metabotropic glutamate receptors as drug targets. Curr Drug Targets. 2007;8 (5) :651-681.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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