PHCCC (Standard)

PHCCC (Standard) is the analytical standard of PHCCC (HY-100409) . This product is intended for research and analytical applications. PHCCC is a Group I mGluR antagonist with an IC50 of 3 μM. PHCCC is a selective positive modulator of mGlu4 receptor. Antiparkinsonian effect[1][2].

Product Specifications

CAS Number

[179068-02-1]

Target

MGluR; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Cancer

Smiles

O=C(C12C(C2)/C(C3=CC=CC=C3O1)=N\O)NC4=CC=CC=C4

Molecular Formula

C17H14N2O3

Molecular Weight

294.31

References & Citations

[1]Marino MJ et al. Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment. Proc Natl Acad Sci U S A. 2003 Nov 11;100 (23) :13668-73.|[2]Récasens M, et al. Metabotropic glutamate receptors as drug targets. Curr Drug Targets. 2007;8 (5) :651-681.