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PF-04979064 (Standard)

PF-04979064 (Standard) is the analytical standard of PF-04979064 (HY-100398) . This product is intended for research and analytical applications. PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with Kis of 0.13 nM and 1.42 nM for PI3Kα and mTOR, respectively.

Product Specifications

CAS Number

[1220699-06-8]

Target

MTOR; PI3K; Reference Standards

Related Pathways

Others; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C(N1C2CCN(C([C@@H](O)C)=O)CC2)N(C)C3=C1C4=NC(C5=CC=C(C)N=C5)=CC=C4N=C3

Molecular Formula

C24H26N6O3

Molecular Weight

446.50

References & Citations

[1]Cheng H et al. Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. ACS Med Chem Lett, 2012 Nov 7, 4 (1) :91-7.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Curated Selection

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