PF-04979064 (Standard)
PF-04979064 (Standard) is the analytical standard of PF-04979064. This product is intended for research and analytical applications. PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with Kis of 0.13 nM and 1.42 nM for PI3Kα and mTOR, respectively.
Product Specifications
CAS Number
1220699-06-8
Target
MTOR; PI3K; Reference Standards
Related Pathways
Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(N1C2CCN(C([C@@H](O)C)=O)CC2)N(C)C3=C1C4=NC(C5=CC=C(C)N=C5)=CC=C4N=C3
Molecular Formula
C24H26N6O3
Molecular Weight
446.50
References & Citations
[1]Cheng H et al. Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. ACS Med Chem Lett, 2012 Nov 7, 4 (1) :91-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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