(S) -ML753286 (Standard)

(S) -ML753286 (Standard) is the analytical standard of (S) -ML753286 (HY-100390) . This product is intended for research and analytical applications. (S) -ML753286 is a breast cancer resistance protein (BCRP) inhibitor with an IC50 of 0.6 μM on BCRP efflux transporter.

Product Specifications

CAS Number

[1699720-85-8]

Target

BCRP; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Cancer

Smiles

COC1=CC=C2C(NC3=C2C[C@]4([H])N(C([C@H](C)NC4=O)=O)[C@H]3CC(C)C)=C1

Molecular Formula

C20H25N3O3

Molecular Weight

355.43

References & Citations

[1]Li Y, et al. Synthesis of a new inhibitor of breast cancer resistance protein with significantly improved pharmacokinetic profiles. Bioorg Med Chem Lett. 2016 Jan 15;26 (2) :551-555.