A 922500 (Standard)
A 922500 (Standard) is the analytical standard of A 922500 (HY-10038) . This product is intended for research and analytical applications. A 922500 (DGAT-1 Inhibitor 4a) is a potent, selective, and orally bioavailable diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of 9 and 22 nM against human and mouse DGAT-1, respectively.
Product Specifications
CAS Number
[959122-11-3]
Target
Acyltransferase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
O=C(NC1=CC=C(C2=CC=C(C([C@@H]3CCC[C@H]3C(O)=O)=O)C=C2)C=C1)NC4=CC=CC=C4
Molecular Formula
C26H24N2O4
Molecular Weight
428.48
References & Citations
[1]King AJ, et al. Diacylglycerol acyltransferase 1 inhibition lowers serum triglycerides in the Zucker fatty rat and the hyperlipidemic hamster. J Pharmacol Exp Ther. 2009 Aug;330 (2) :526-31.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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