FPTQ (Standard)
FPTQ (Standard) is the analytical standard of FPTQ. This product is intended for research and analytical applications. FPTQ is potent mGluR1 antagonist with IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively[1]. FPTQ has anti-oxidant and anti-inflammatory effects in vitro and in vivo[2].
Product Specifications
CAS Number
864863-72-9
Target
MGluR; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Others
Smiles
FC(N=CC=C1)=C1N2N=NC(C3=CC4=C(C=C3)N=CC=C4)=C2C
Molecular Formula
C17H12FN5
Molecular Weight
305.31
References & Citations
[1]Fujinaga M et al. Synthesis and evaluation of 6-[1- (2-[ (18) F]fluoro-3-pyridyl) -5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain. Bioorg Med Chem, 2011 Jan 1, 19 (1) :102-10.|[2]Geum Ran Kim, et al. Anti-inflammatory effect of a novel synthetic compound 1- ((4-fluorophenyl) thio) isoquinoline in RAW264.7 macrophages and a zebrafish model. Fish Shellfish Immunol. 2019 Apr;87:395-400.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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