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MELK-8a (hydrochloride) (Standard)

MELK-8a (hydrochloride) (Standard) is the analytical standard of MELK-8a (hydrochloride) (HY-100368A) . This product is intended for research and analytical applications. MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM.

Product Specifications

CAS Number

[2096992-20-8]

Target

MELK; Reference Standards

Related Pathways

Others; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

CN(CC1)CCN1C2=CC=C(N3C=C(C4=CC=NC=C4OCC5CCNCC5)C=N3)C=C2.Cl

Molecular Formula

C25H33ClN6O

Molecular Weight

469.02

References & Citations

[1]Touré BB, et al. Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. J Med Chem. 2016 May 26;59 (10) :4711-23.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Curated Selection

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