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BI-9564 (Standard)

BI-9564 (Standard) is the analytical standard of BI-9564. This product is intended for research and analytical applications. BI-9564, a chemical probe, is a potent, selective and cell-permeable BRD9/BRD7 bromodomains inhibitor, with IC50s of 75 nM and 3.4 μM and Kds of 14 nM and 239 nM, respectively. BI-9564 has an IC50 of > 100 μM for BET family[1].

Product Specifications

CAS Number

1883429-22-8

Target

Epigenetic Reader Domain; Reference Standards

Related Pathways

Epigenetics; Others

Field of Research

Cancer

Smiles

CN(C)CC1=CC(OC)=C(C(C2=C3C=NC=C2)=CN(C)C3=O)C=C1OC

Molecular Formula

C20H23N3O3

Molecular Weight

353.41

References & Citations

[1]Martin LJ, et al. Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem. 2016 May 26;59 (10) :4462-75.|[2]Rezaul M. Karim, et al. An Advanced Tool To Interrogate BRD9. J. Med. Chem., 2016, 59 (10), pp 4459-4461

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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