CA-074 methyl ester (Standard)
CA-074 methyl ester (Standard) is the analytical standard of CA-074 methyl ester (HY-100350) . This product is intended for research and analytical applications. CA-074 methyl ester is a specific inhibitor of Cathepsin B, which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects.
Product Specifications
CAS Number
[147859-80-1]
Target
Cathepsin; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Neurological Disease; Cancer
Smiles
O=C([C@@H]1[C@@H](C(NCCC)=O)O1)N[C@]([C@@H](C)CC)([H])C(N(CCC2)[C@@H]2C(OC)=O)=O
Molecular Formula
C19H31N3O6
Molecular Weight
397.47
References & Citations
[1]Xu Y, et al. Protective mechanisms of CA074-me (other than cathepsin-B inhibition) against programmed necrosis induced by global cerebral ischemia/reperfusion injury in rats. Brain Res Bull. 2016 Jan;120:97-105|[2]Patel N, et al. CA-074Me compound inhibits osteoclastogenesis via suppression of the NFATc1 and c-FOS signaling pathways. J Orthop Res. 2015 Oct;33 (10) :1474-86|[3]Zhang L, et al. Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis. Lab Invest. 2015 Jan;95 (1) :65-77
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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