M2I-1 (Standard)
M2I-1 (Standard) is the analytical standard of M2I-1. This product is intended for research and analytical applications. M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC).
Product Specifications
CAS Number
312271-03-7
Target
Checkpoint Kinase (Chk) ; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Smiles
O=C(/C(C(N1)=O)=C\C2=CC=C(N(CC(C)C)CC(C)C)C([N+]([O-])=O)=C2)NC1=S
Molecular Formula
C19H24N4O4S
Molecular Weight
404.48
References & Citations
[1]Johanna Kastl et al. Mad2 Inhibitor-1 (M2I-1) : A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chem. Biol., 2015, 10 (7), pp 1661-1666.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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