M2I-1 (Standard)

M2I-1 (Standard) is the analytical standard of M2I-1 (HY-100341) . This product is intended for research and analytical applications. M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC) [1].

Product Specifications

CAS Number

[312271-03-7]

Target

Checkpoint Kinase (Chk) ; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Others

Smiles

O=C(/C(C(N1)=O)=C\C2=CC=C(N(CC(C)C)CC(C)C)C([N+]([O-])=O)=C2)NC1=S

Molecular Formula

C19H24N4O4S

Molecular Weight

404.48

References & Citations

[1]Johanna Kastl et al. Mad2 Inhibitor-1 (M2I-1) : A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chem. Biol., 2015, 10 (7), pp 1661-1666.