XL 999 (Standard)
XL 999 (Standard) is the analytical standard of XL 999 (HY-100315) . This product is intended for research and analytical applications. XL999 is a multi-target tyrosine kinase inhibitor. XL999 has IC50 values for KDR, Flt-1, FGFR1 and PDGFRα of 4 nM, 20 nM, 4 nM and 2 nM, respectively. XL999 can be used in the research of cancer[1].
Product Specifications
CAS Number
[705946-27-6]
Target
FGFR; PDGFR; Reference Standards; VEGFR
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Cardiovascular Disease
Smiles
O=C1NC2=C(C=C(NC3CCN(CC)CC3)C=C2)/C1=C(C4=CC=CC(F)=C4)/C5=NC=C(C)N5
Molecular Formula
C26H28FN5O
Molecular Weight
445.53
References & Citations
[1]Moon K, et al. The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 22 (2012) 4979–4985
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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