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XL 999 (Standard)

XL 999 (Standard) is the analytical standard of XL 999. This product is intended for research and analytical applications. XL999 is a multi-target tyrosine kinase inhibitor. XL999 has IC50 values for KDR, Flt-1, FGFR1 and PDGFRα of 4 nM, 20 nM, 4 nM and 2 nM, respectively. XL999 can be used in the research of cancer[1].

Product Specifications

CAS Number

705946-27-6

Target

FGFR; PDGFR; Reference Standards; VEGFR

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer; Cardiovascular Disease

Smiles

O=C1NC2=C(C=C(NC3CCN(CC)CC3)C=C2)/C1=C(C4=CC=CC(F)=C4)/C5=NC=C(C)N5

Molecular Formula

C26H28FN5O

Molecular Weight

445.53

References & Citations

[1]Moon K, et al. The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 22 (2012) 4979–4985

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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