Caldaret (Standard)

Caldaret (Standard) is the analytical standard of Caldaret (HY-100298) . This product is intended for research and analytical applications. Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.

Product Specifications

CAS Number

[133804-44-1]

Target

Na+/Ca2+ Exchanger; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Cardiovascular Disease

Smiles

O=S(C1=CC(C)=CC=C1N2CCNCC2)(O)=O

Molecular Formula

C11H16N2O3S

Molecular Weight

256.32

References & Citations

[1]Kawasumi H, et al. Caldaret, an intracellular Ca2+ handling modulator, limits infarct size of reperfused canine heart. J Pharmacol Sci. 2007 Feb;103 (2) :222-33.|[2]Satoh N, et al. Lusitropic effect of MCC-135 is associated with improvement of sarcoplasmic reticulum function in ventricular muscles of rats with diabetic cardiomyopathy. J Pharmacol Exp Ther. 2001 Sep;298 (3) :1161-6.