Org41841 (Standard)

Org41841 (Standard) is the analytical standard of Org41841 (HY-100271) . This product is intended for research and analytical applications. Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC50s of 0.2 and 7.7 μM, respectively.

Product Specifications

CAS Number

[301847-37-0]

Target

Reference Standards; TSH Receptor

Related Pathways

GPCR/G Protein; Others

Field of Research

Endocrinology

Smiles

O=C(C1=C(N)C2=C(C3=CC=CC(OC)=C3)N=C(SC)N=C2S1)NC(C)(C)C

Molecular Formula

C19H22N4O2S2

Molecular Weight

402.53

References & Citations

[1]Holger Jaschke, et al. A low molecular weight agonist signals by binding to the transmembrane domain of thyroid-stimulating hormone receptor (TSHR) and luteinizing hormone/chorionic gonadotropin receptor (LHCGR) . J Biol Chem. 2006 Apr 14;281 (15) :9841-4.