XEN723 (Standard)
XEN723 (Standard) is the analytical standard of XEN723. This product is intended for research and analytical applications. XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.
Product Specifications
CAS Number
1072803-08-7
Target
Reference Standards; Stearoyl-CoA Desaturase (SCD)
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
O=C(C1=C(C)N=C(N2CCN(CC3=CC=C(F)C=C3)C2=O)S1)NCC4=CC=CN=C4
Molecular Formula
C21H20FN5O2S
Molecular Weight
425.48
References & Citations
[1]Sun S, et al. Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases. Bioorg Med Chem Lett. 2014 Jan 15;24 (2) :520-5.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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