XEN723 (Standard)

XEN723 (Standard) is the analytical standard of XEN723 (HY-100249) . This product is intended for research and analytical applications. XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively.

Product Specifications

CAS Number

[1072803-08-7]

Target

Reference Standards; Stearoyl-CoA Desaturase (SCD)

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O=C(C1=C(C)N=C(N2CCN(CC3=CC=C(F)C=C3)C2=O)S1)NCC4=CC=CN=C4

Molecular Formula

C21H20FN5O2S

Molecular Weight

425.48

References & Citations

[1]Sun S, et al. Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases. Bioorg Med Chem Lett. 2014 Jan 15;24 (2) :520-5.