NS1652 (Standard)
NS1652 (Standard) is the analytical standard of NS1652. This product is intended for research and analytical applications. NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells.
Product Specifications
CAS Number
1566-81-0
Target
Chloride Channel; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Neurological Disease
Smiles
O=C(O)C1=CC=CC=C1NC(NC2=CC=CC(C(F)(F)F)=C2)=O
Molecular Formula
C15H11F3N2O3
Molecular Weight
324.25
References & Citations
[1]Kjaer K, et al. Chloride channel blockers inhibit iNOS expression and NO production in IFNgamma-stimulated microglial BV2 cells. Brain Res. 2009 Jul 24;1281:15-24.|[2]Bennekou P, et al. Volume control in sickle cells is facilitated by the novel anion conductance inhibitor NS1652. Blood. 2000 Mar 1;95 (5) :1842-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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