NS1652 (Standard)

NS1652 (Standard) is the analytical standard of NS1652 (HY-100244) . This product is intended for research and analytical applications. NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells.

Product Specifications

CAS Number

[1566-81-0]

Target

Chloride Channel; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Neurological Disease

Smiles

O=C(O)C1=CC=CC=C1NC(NC2=CC=CC(C(F)(F)F)=C2)=O

Molecular Formula

C15H11F3N2O3

Molecular Weight

324.25

References & Citations

[1]Kjaer K, et al. Chloride channel blockers inhibit iNOS expression and NO production in IFNgamma-stimulated microglial BV2 cells. Brain Res. 2009 Jul 24;1281:15-24.|[2]Bennekou P, et al. Volume control in sickle cells is facilitated by the novel anion conductance inhibitor NS1652. Blood. 2000 Mar 1;95 (5) :1842-8.