ML133 (hydrochloride) (Standard)
ML133 (hydrochloride) (Standard) is the analytical standard of ML133 (hydrochloride) (HY-100230A) . This product is intended for research and analytical applications. ML133 hydrochloride is a selective Kir2 family channels inhibitor, with an IC50 of 1.8 μM at pH 7.4 and 290 nM at pH 8.5[1].
Product Specifications
CAS Number
[1222781-70-5]
Target
Potassium Channel; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Others
Smiles
COC1=CC=C(CNCC2=C3C=CC=CC3=CC=C2)C=C1.[H]Cl
Molecular Formula
C19H20ClNO
Molecular Weight
313.82
References & Citations
[1]Wang HR, et al. Selective inhibition of the K (ir) 2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133. ACS Chem Biol. 2011 Aug 19;6 (8) :845-56.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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