SANT-1 (Standard)
SANT-1 (Standard) is the analytical standard of SANT-1 (HY-100224) . This product is intended for research and analytical applications. SANT-1, a potent Smo antagonist, inhibits Hedgehog signaling. SANT-1 shows IC50s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 assay, respectively[1].
Product Specifications
CAS Number
[304909-07-7]
Target
Hedgehog; Reference Standards; Smo
Related Pathways
Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
CC1=C(/C=N/N2CCN(CC3=CC=CC=C3)CC2)C(C)=NN1C4=CC=CC=C4
Molecular Formula
C23H27N5
Molecular Weight
373.49
References & Citations
[1]Chen JK, et al. Small molecule modulation of Smoothened activity. Proc Natl Acad Sci U S A. 2002 Oct 29;99 (22) :14071-6.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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