Calpeptin (Standard)
Calpeptin (Standard) is the analytical standard of Calpeptin. This product is intended for research and analytical applications. Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets[1]. Calpeptin is also an inhibitor of cathepsin K[2].
Product Specifications
CAS Number
117591-20-5
UNSPSC
12352005
Target
Apoptosis; Cathepsin; Proteasome; Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(OCC1=CC=CC=C1)N[C@H](C(N[C@H](C=O)CCCC)=O)CC(C)C
Molecular Formula
C20H30N2O4
Molecular Weight
362.46
References & Citations
[1]Tsujinaka T, et al. Synthesis of a new cell penetrating calpain inhibitor (calpeptin) . Biochem Biophys Res Commun. 1988 Jun 30;153 (3) :1201-8.|[2]Catalano JG, et al. Design of small molecule ketoamide-based inhibitors of cathepsin K. Bioorg Med Chem Lett. 2004 Feb 9;14 (3) :719-22.|[3]Tabata C, et al. The calpain inhibitor calpeptin prevents pulmonary fibrosis in mice. Clin Exp Immunol. 2010 Dec;162 (3) :560-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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