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CZ415 (Standard)

CZ415 (Standard) is the analytical standard of CZ415 (HY-100222) . This product is intended for research and analytical applications. CZ415 is a potent and highly selective mTOR inhibitor with a pIC50 of 8.07. CZ415 inhibits mTORC1 and mTORC2 protein complex.

Product Specifications

CAS Number

[1429639-50-8]

Target

MTOR; Reference Standards

Related Pathways

Others; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C(NCC)NC(C=C1)=CC=C1C2=NC3=C(CS(C3(C)C)(=O)=O)C(N4[C@@H](C)COCC4)=N2

Molecular Formula

C22H29N5O4S

Molecular Weight

459.56

References & Citations

[1]Cansfield AD, et al. CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model. ACS Med Chem Lett. 2016 Jun 10;7 (8) :768-73.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Curated Selection

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