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AM-2394 (Standard)

AM-2394 (Standard) is the analytical standard of AM-2394 (HY-100221) . This product is intended for research and analytical applications. AM-2394 is a structurally distinct glucokinase activator (GKA) . AM-2394 activates glucokinase (GK) with an EC50 of 60 nM.

Product Specifications

Target

Glucokinase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O=C(NC)NC1=CC(OC2=CC(C)=CN=C2)=C(C3=CC=C(OCC(C)(O)C)N=C3)C=N1

Molecular Formula

C22H25N5O4

Molecular Weight

423.47

References & Citations

[1]Dransfield PJ, et al. Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394. ACS Med Chem Lett. 2016 May 23;7 (7) :714-8.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100221R/

Scientific Category

Reference Standards

CAS Number

[1442684-77-6]

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