AM-2394 (Standard)
AM-2394 (Standard) is the analytical standard of AM-2394 (HY-100221) . This product is intended for research and analytical applications. AM-2394 is a structurally distinct glucokinase activator (GKA) . AM-2394 activates glucokinase (GK) with an EC50 of 60 nM.
Product Specifications
CAS Number
[1442684-77-6]
Target
Glucokinase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
O=C(NC)NC1=CC(OC2=CC(C)=CN=C2)=C(C3=CC=C(OCC(C)(O)C)N=C3)C=N1
Molecular Formula
C22H25N5O4
Molecular Weight
423.47
References & Citations
[1]Dransfield PJ, et al. Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394. ACS Med Chem Lett. 2016 May 23;7 (7) :714-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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