CP21R7 (Standard)
CP21R7 (Standard) is the analytical standard of CP21R7 (HY-100207) . This product is intended for research and analytical applications. CP21R7 is potent GSK-3β inhibitor, with an IC50 of 1.8 nM; CP21R7 also shows inhibitory activitiy against PKCα, with an IC50 of 1900 nM.
Product Specifications
CAS Number
[125314-13-8]
Target
GSK-3; Reference Standards
Related Pathways
Others; PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C1C(C2=CN(C)C3=CC=CC=C23)=C(C4=CC(N)=CC=C4)C(N1)=O
Molecular Formula
C19H15N3O2
Molecular Weight
317.34
References & Citations
[1]Gong L, et al. Discovery of potent and bioavailable GSK-3beta inhibitors. Bioorg Med Chem Lett. 2010 Mar 1;20 (5) :1693-6.|[2]Patsch C, et al. Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells. Nat Cell Biol. 2015 Aug;17 (8) :994-1003.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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