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PF-04991532 (Standard)

PF-04991532 (Standard) is the analytical standard of PF-04991532. This product is intended for research and analytical applications. PF-04991532 is a potent, hepatoselective glucokinase activator with EC50s of 80 and 100 nM in human and rat, respectively.

Product Specifications

CAS Number

1215197-37-7

Target

Glucokinase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O=C(C1=CC=C(NC([C@@H](N2C=C(C(F)(F)F)N=C2)CC3CCCC3)=O)N=C1)O

Molecular Formula

C18H19F3N4O3

Molecular Weight

396.36

References & Citations

[1]Erion DM, et al. The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats. PLoS One. 2014 May 23;9 (5) :e97139.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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