PF-04991532 (Standard)
PF-04991532 (Standard) is the analytical standard of PF-04991532 (HY-100181) . This product is intended for research and analytical applications. PF-04991532 is a potent, hepatoselective glucokinase activator with EC50s of 80 and 100 nM in human and rat, respectively.
Product Specifications
CAS Number
[1215197-37-7]
Target
Glucokinase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
O=C(C1=CC=C(NC([C@@H](N2C=C(C(F)(F)F)N=C2)CC3CCCC3)=O)N=C1)O
Molecular Formula
C18H19F3N4O3
Molecular Weight
396.36
References & Citations
[1]Erion DM, et al. The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats. PLoS One. 2014 May 23;9 (5) :e97139.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100181R/
Scientific Category
Reference Standards
Curated Selection
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