PF-4878691 (Standard)
PF-4878691 (Standard) is the analytical standard of PF-4878691. This product is intended for research and analytical applications. PF-4878691 (3M-852A) is an orally active TLR7 agonist. PF-4878691 has the innate immune response activity, antiviral efficacy against HCV, and can be used for the research of cancer[1][2].
Product Specifications
CAS Number
532959-63-0
Product Name Alternative
3M-852A (Standard)
UNSPSC
12352005
Target
Apoptosis; HCV; Interleukin Related; Reference Standards; TNF Receptor; Toll-like Receptor (TLR)
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Others
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
CS(=O)(NCCCCN1C(CC)=NC2=C1C3=CC=CC=C3N=C2N)=O
Molecular Formula
C17H23N5O2S
Molecular Weight
361.46
References & Citations
[1]Fidock MD, et al. The innate immune response, clinical outcomes, and ex vivo HCV antiviral efficacy of a TLR7 agonist (PF-4878691) . Clin Pharmacol Ther. 2011 Jun;89 (6) :821-9.|[2]Horscroft NJ, et al. Antiviral applications of Toll-like receptor agonists. J Antimicrob Chemother. 2012 Apr;67 (4) :789-801.|[3]Birmachu W, et al. Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists [J]. BMC immunology, 2007, 8: 1-19.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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