AP521 (Standard)

AP521 (Standard) is the analytical standard of AP521. This product is intended for research and analytical applications. AP521 is an agonist of human 5-HT1A receptor with an IC50 of 94 nM.

Product Specifications

CAS Number

151227-08-6

Target

5-HT Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

O=C([C@H]1CC(C2=CC=CC=C2S3)=C3CN1)NCC4=CC=C(OCO5)C5=C4.[H]Cl

Molecular Formula

C20H19ClN2O3S

Molecular Weight

402.89

References & Citations

[1]Kasahara K, et al. The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats. J Pharmacol Sci. 2015 Jan;127 (1) :109-16.