SDZ-MKS 492 (Standard)
SDZ-MKS 492 (Standard) is the analytical standard of SDZ-MKS 492 (HY-100164) . This product is intended for research and analytical applications. SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE) . SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF) -induced bronchoconstriction and allergic reactions in guinea pigs and rats[1].
Product Specifications
CAS Number
[114606-56-3]
Target
Phosphodiesterase (PDE) ; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(N1C)N(C)C2=C(N(CCOC)C(N[C@H](C3=CC=C(OC)C(OC)=C3)CO)=N2)C1=O
Molecular Formula
C20H27N5O6
Molecular Weight
433.46
References & Citations
[1]Nagai H, et al. Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats. Jpn J Pharmacol. 1993 Dec;63 (4) :405-13.|[2]Morley J, et, al. SDZ MKS 492. Agents Actions Suppl. 1991;34:403-10.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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