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SDZ-MKS 492 (Standard)

SDZ-MKS 492 (Standard) is the analytical standard of SDZ-MKS 492. This product is intended for research and analytical applications. SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF) -induced bronchoconstriction and allergic reactions in guinea pigs and rats[1].

Product Specifications

CAS Number

114606-56-3

Target

Phosphodiesterase (PDE) ; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology

Smiles

O=C(N1C)N(C)C2=C(N(CCOC)C(N[C@H](C3=CC=C(OC)C(OC)=C3)CO)=N2)C1=O

Molecular Formula

C20H27N5O6

Molecular Weight

433.46

References & Citations

[1]Nagai H, et al. Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats. Jpn J Pharmacol. 1993 Dec;63 (4) :405-13.|[2]Morley J, et, al. SDZ MKS 492. Agents Actions Suppl. 1991;34:403-10.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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