4-IBP (Standard)
4-IBP (Standard) is the analytical standard of 4-IBP. This product is intended for research and analytical applications. 4-IBP is a selective σ₁ receptor agonist with high affinity for the σ₁ receptor (Ki =1.7 nM) and moderate affinity for the σ₂ receptor (Ki = 25.2 nM). 4-IBP can make cancer cells more sensitive to the cytotoxic effects of pro-apoptotic and pro-autophagic compounds. 4-IBP significantly reduces the migration ability of a variety of cancer cells. 4-IBP is mainly used in glioblastoma, non-small cell lung cancer and prostate cancer research[1][2][3][4][5][6].
Product Specifications
CAS Number
155798-08-6
Target
Apoptosis; Autophagy; Reference Standards; Sigma Receptor
Related Pathways
Apoptosis; Autophagy; Neuronal Signaling; Others
Field of Research
Cancer
Smiles
O=C(NC1CCN(CC2=CC=CC=C2)CC1)C3=CC=C(I)C=C3
Molecular Formula
C19H21IN2O
Molecular Weight
420.29
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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