(Rac) -SCH 563705 (Standard)
(Rac) -SCH 563705 (Standard) is the analytical standard of (Rac) -SCH 563705. This product is intended for research and analytical applications. (Rac) -SCH 563705 is a racemic mixture of SCH 563705 (HY-10011). SCH 563705 (compound 16) is a potent and orally active CXCR2 and CXCR1 antagonist with IC50 values of 1.3 nM and 7.3 nM and Ki values of 1 nM and 3 nM, respectively[1][2].
Product Specifications
CAS Number
2701435-64-3
Target
CXCR; Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Others
Field of Research
Endocrinology; Inflammation/Immunology
Smiles
O=C(C(NC1=CC=CC(C(N(C)C)=O)=C1O)=C2NC(CC)C3=CC(C(C)C)=CO3)C2=O
Molecular Formula
C23H27N3O5
Molecular Weight
425.48
References & Citations
[1]Min S H, et al. Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis[J]. Biochemical and biophysical research communications, 2010, 391 (1) : 1080-1086.|[2]Chao J, et al. C (4) -alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists[J]. Bioorganic & medicinal chemistry letters, 2007, 17 (13) : 3778-3783.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC041799-100 1x 100 µL
P53 Tumor Suppressor Protein (TP53/1799R), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
RDR-HMG1-p-01 96 Tests
Porcine High Mobility Group Protein 1 (HMG1) ELISA Kit
Sign In for Pricing
View Details RDR-HMG1-p-02 48 Tests
Porcine High Mobility Group Protein 1 (HMG1) ELISA Kit
Sign In for Pricing
View Details 