TA-02 (Standard)
TA-02 (Standard) is the analytical standard of TA-02. This product is intended for research and analytical applications. TA-02, an analog of SB 203580 (HY-10256), is a p38 MAPK inhibitor with an IC50 of 20 nM. TA-02 especially inhibits TGFBR-2. TA-02 exhibits similar cardiogenic properties as SB 203580 and SB 202190 (HY-10295).
Product Specifications
CAS Number
1784751-19-4
Target
Autophagy; p38 MAPK; Reference Standards
Related Pathways
Autophagy; MAPK/ERK Pathway; Others
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Smiles
FC(C=C1)=CC=C1C2=C(C3=CC=NC=C3)NC(C4=CC=CC=C4F)=N2
Molecular Formula
C20H13F2N3
Molecular Weight
333.33
References & Citations
[1]Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.|[2]Jiedong Liang, et al. The activation of BDNF reduced inflammation in a spinal cord injury model by TrkB/p38 MAPK signaling. Exp Ther Med. 2019 Mar;17 (3) :1688-1696.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040149-100 1x 100 µL
CD106 / VCAM1 (1.4C3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042848-100 1x 100 µL
Fibronectin (Fn-3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942110-100 1x 100 µL
PTEN (Tumor Suppressor Oncoprotein) (PTEN/2110), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041803-100 1x 100 µL
GP2 (Glycoprotein 2) / ZAP75 (GP2/1803), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details