GLX351322 (Standard)
GLX351322 (Standard) is the analytical standard of GLX351322 (HY-100111) . This product is intended for research and analytical applications. GLX351322 is an inhibitor of NADPH oxidase 4 (Nox4), and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM.
Product Specifications
CAS Number
[835598-94-2]
Target
NADPH Oxidase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
O=C(OCC)C1=C(SC2=C1CCC2)NC(CN3CCN(CC3)C(C4=CC=CO4)=O)=O
Molecular Formula
C21H25N3O5S
Molecular Weight
431.51
References & Citations
[1]Anvari E, et al. The novel NADPH oxidase 4 inhibitor GLX351322 counteracts glucose intolerance in high-fat diet-treated C57BL/6 mice. Free Radic Res. 2015;49 (11) :1308-18.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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