A-887826 (Standard)
A-887826 (Standard) is the analytical standard of A-887826 (HY-100080) . This product is intended for research and analytical applications. A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na (v) 1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo[1].
Product Specifications
CAS Number
[1266212-81-0]
Target
Reference Standards; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Neurological Disease
Smiles
O=C(C1=CC(C2=CC=C(OCCCC)C(Cl)=C2)=CN=C1)NCC3=CC=CN=C3N4CCOCC4
Molecular Formula
C26H29ClN4O3
Molecular Weight
480.99
References & Citations
[1]Zhang XF, et al. A-887826 is a structurally novel, potent and voltage-dependent Na (v) 1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats. Neuropharmacology. 2010 Sep;59 (3) :201-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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