Nα, Nα-Bis (carboxymethyl) -L-lysine (Standard)

Nα, Nα-Bis (carboxymethyl) -L-lysine (Standard) is the analytical standard of Nα, Nα-Bis (carboxymethyl) -L-lysine (HY-100047) . This product is intended for research and analytical applications. Nα, Nα-Bis (carboxymethyl) -L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα, Nα-Bis (carboxymethyl) -L-lysine can be used in bitter receptors related study[1][2][3].

Product Specifications

CAS Number

[113231-05-3]

Target

Reference Standards; Taste Receptor

Related Pathways

GPCR/G Protein; Others

Field of Research

Others

Smiles

NCCCC[C@@H](C(O)=O)N(CC(O)=O)CC(O)=O

Molecular Formula

C10H18N2O6

Molecular Weight

262.26

References & Citations

[1]Pydi SP, et al. Amino acid derivatives as bitter taste receptor (T2R) blockers. J Biol Chem. 2014;289 (36) :25054-25066. |[2]Sidhu C, et al. Regulation of Rac1 GTPase activity by quinine through G-protein and bitter taste receptor T2R4. Mol Cell Biochem. 2017;426 (1-2) :129-136. |[3]Masamoto M, et al. Yoshida R. Effects of bitter receptor antagonists on behavioral lick responses of mice. Neurosci Lett. 2020;730:135041.