PD 117519 (Standard)

PD 117519 (Standard) is the analytical standard of PD 117519 (HY-100032) . This product is intended for research and analytical applications. PD 117519 (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models[1][2].

Product Specifications

CAS Number

[96392-15-3]

Target

Adenosine Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Others

Field of Research

Neurological Disease

Smiles

OC[C@@H](O1)[C@@H](O)[C@@H](O)[C@@H]1N2C=NC3=C2N=CN=C3NC4CC(C=CC=C5)=C5C4

Molecular Formula

C19H21N5O4

Molecular Weight

383.40

References & Citations

[1]Reynolds DL, et al. Liquid chromatographic analysis of the adenosine agonist PD 117519 in dog plasma. J Pharm Biomed Anal. 1991;9 (4) :345-9.|[2]Tobin GA, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014 Jun;42 (4) :709-24.|[3]Enerson BE, et al. Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression. Toxicol Pathol. 2006;34 (1) :27-32.