PD 117519 (Standard)
PD 117519 (Standard) is the analytical standard of PD 117519. This product is intended for research and analytical applications. PD 117519 (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models[1][2].
Product Specifications
CAS Number
96392-15-3
Target
Adenosine Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Neurological Disease
Smiles
OC[C@@H](O1)[C@@H](O)[C@@H](O)[C@@H]1N2C=NC3=C2N=CN=C3NC4CC(C=CC=C5)=C5C4
Molecular Formula
C19H21N5O4
Molecular Weight
383.40
References & Citations
[1]Reynolds DL, et al. Liquid chromatographic analysis of the adenosine agonist PD 117519 in dog plasma. J Pharm Biomed Anal. 1991;9 (4) :345-9.|[2]Tobin GA, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014 Jun;42 (4) :709-24.|[3]Enerson BE, et al. Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression. Toxicol Pathol. 2006;34 (1) :27-32.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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