HLCL-61 (hydrochloride) (Standard)

HLCL-61 (hydrochloride) (Standard) is the analytical standard of HLCL-61 (hydrochloride) (HY-100025A) . This product is intended for research and analytical applications. HLCL-61 hydrochloride is a first-in-class inhibitor of protein arginine methyltransferase 5 (PRMT5) .

Product Specifications

CAS Number

[1158279-20-9]

Target

Apoptosis; Histone Methyltransferase; Reference Standards

Related Pathways

Apoptosis; Epigenetics; Others

Field of Research

Cancer

Smiles

[H]Cl.COC1=CC=CC=C1CNCC2=CC3=C(C=C2)N(CC)C4=C3C=CC=C4

Molecular Formula

C23H25ClN2O

Molecular Weight

380.91

References & Citations

[1]Tarighat SS, et al. The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation. Leukemia. 2016 Apr;30 (4) :789-99.