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BAY-1436032 (Standard)

BAY-1436032 (Standard) is the analytical standard of BAY-1436032 (HY-100020) . This product is intended for research and analytical applications. BAY-1436032 is a novel pan-mutant isocitrate dehydrogenase 1 (IDH1) inhibitor.

Product Specifications

CAS Number

[1803274-65-8]

Target

Isocitrate Dehydrogenase (IDH) ; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C(O)CCC1=CC=C2C(N=C(NC3=CC=C(OC(F)(F)F)C=C3)N2[C@H]4CC(C)(C)C[C@@H](C)C4)=C1

Molecular Formula

C26H30F3N3O3

Molecular Weight

489.53

References & Citations

[1]Chaturvedi A, et al. Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo. Leukemia. 2017 Oct;31 (10) :2020-2028.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Curated Selection

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