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BAY1125976 (Standard)

BAY1125976 (Standard) is the analytical standard of BAY1125976. This product is intended for research and analytical applications. BAY1125976, a chemical probe, is a selective allosteric Akt1/Akt2 inhibitor; inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively.

Product Specifications

CAS Number

1402608-02-9

Target

Akt; Reference Standards

Related Pathways

Others; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C(C1=NN2C(C=C1)=NC(C3=CC=C(C4(N)CCC4)C=C3)=C2C5=CC=CC=C5)N

Molecular Formula

C23H21N5O

Molecular Weight

383.45

References & Citations

[1]Politz O, et al. BAY 1125976, a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models. Int J Cancer. 2017 Jan 15;140 (2) :449-459.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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