AZD0156 (Standard)
AZD0156 (Standard) is the analytical standard of AZD0156. This product is intended for research and analytical applications. AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits the ATM-mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis[1].
Product Specifications
CAS Number
1821428-35-6
Target
Apoptosis; ATM/ATR; Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3
Molecular Formula
C26H31N5O3
Molecular Weight
461.56
References & Citations
[1]Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer.?
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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