AZD0156 (Standard)
AZD0156 (Standard) is the analytical standard of AZD0156. This product is intended for research and analytical applications. AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits the ATM-mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis[1].
Product Specifications
CAS Number
1821428-35-6
Target
Apoptosis; ATM/ATR; Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3
Molecular Formula
C26H31N5O3
Molecular Weight
461.56
References & Citations
[1]Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer.?
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6279399-01 0.2 mL
C10orf58, CT (FAM213A, C10orf58, PAMM, Redox-regulatory protein FAM213A, Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (FITC)
Sign In for Pricing
View Details MBS6279399-02 5x 0.2 mL
C10orf58, CT (FAM213A, C10orf58, PAMM, Redox-regulatory protein FAM213A, Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (FITC)
Sign In for Pricing
View Details