Mivebresib (Standard)
Mivebresib (Standard) is the analytical standard of Mivebresib. This product is intended for research and analytical applications. Mivebresib (ABBV-075) is a potent and orally active bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a Ki of 1.5 nM[1].
Product Specifications
CAS Number
1445993-26-9
Product Name Alternative
ABBV-075 (Standard)
UNSPSC
12352005
Target
Apoptosis; Epigenetic Reader Domain; Reference Standards
Related Pathways
Apoptosis; Epigenetics; Others
Field of Research
Cancer
Smiles
CCS(=O)(NC1=CC=C(OC2=CC=C(F)C=C2F)C(C3=CN(C)C(C4=C3C=CN4)=O)=C1)=O
Molecular Formula
C22H19F2N3O4S
Molecular Weight
459.47
References & Citations
[1]EJ Faivre et al. Abstract 4694: ABBV-075, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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