Mivebresib (Standard)

Mivebresib (Standard) is the analytical standard of Mivebresib. This product is intended for research and analytical applications. Mivebresib (ABBV-075) is a potent and orally active bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a Ki of 1.5 nM[1].

Product Specifications

CAS Number

[1445993-26-9]

Product Name Alternative

ABBV-075 (Standard)

UNSPSC

12352005

Target

Apoptosis; Epigenetic Reader Domain; Reference Standards

Related Pathways

Apoptosis; Epigenetics; Others

Field of Research

Cancer

Smiles

CCS(=O)(NC1=CC=C(OC2=CC=C(F)C=C2F)C(C3=CN(C)C(C4=C3C=CN4)=O)=C1)=O

Molecular Formula

C22H19F2N3O4S

Molecular Weight

459.47

References & Citations

[1]EJ Faivre et al. Abstract 4694: ABBV-075, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo