(1S,2S) -2-PCCA (hydrochloride) (Standard)
(1S,2S) -2-PCCA (hydrochloride) (Standard) is the analytical standard of (1S,2S) -2-PCCA (hydrochloride). This product is intended for research and analytical applications. (1S,2S) -2-PCCA hydrochloride is a less active diastereomer of 2-PCCA. 2-PCCA is a GPR88 receptor agonist, and inhibits GPR88-mediated cAMP production, with an EC50 of 116 nM in HEK293 cells.
Product Specifications
CAS Number
1609563-70-3
Target
Drug Isomer; GPR88; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Neurological Disease
Smiles
CC[C@H](C)[C@H](N)CN(C1=CC=C(C2=CC=C(C=C2)CCC)C=C1)C([C@@H]3[C@@H](C4=CC=CC=N4)C3)=O.Cl.Cl
Molecular Formula
C30H39Cl2N3O
Molecular Weight
528.56
References & Citations
[1]Jin C, et al. Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor. ACS Chem Neurosci. 2014 Jul 16;5 (7) :576-87.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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