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(1S,2S) -2-PCCA (hydrochloride) (Standard)

(1S,2S) -2-PCCA (hydrochloride) (Standard) is the analytical standard of (1S,2S) -2-PCCA (hydrochloride) (HY-100013B1) . This product is intended for research and analytical applications. (1S,2S) -2-PCCA hydrochloride is a less active diastereomer of 2-PCCA. 2-PCCA is a GPR88 receptor agonist, and inhibits GPR88-mediated cAMP production, with an EC50 of 116 nM in HEK293 cells.

Product Specifications

CAS Number

[1609563-70-3]

Target

Drug Isomer; GPR88; Reference Standards

Related Pathways

GPCR/G Protein; Others

Field of Research

Neurological Disease

Smiles

CC[C@H](C)[C@H](N)CN(C1=CC=C(C2=CC=C(C=C2)CCC)C=C1)C([C@@H]3[C@@H](C4=CC=CC=N4)C3)=O.Cl.Cl

Molecular Formula

C30H39Cl2N3O

Molecular Weight

528.56

References & Citations

[1]Jin C, et al. Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor. ACS Chem Neurosci. 2014 Jul 16;5 (7) :576-87.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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