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Fumarate hydratase-IN-2 (sodium salt) (Standard)

Fumarate hydratase-IN-2 (sodium salt) (Standard) is the analytical standard of Fumarate hydratase-IN-2 (sodium salt) (HY-100005A) . This product is intended for research and analytical applications. Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor (Ki=4.5 μM) with nutrient-dependent cytotoxicity [1].

Product Specifications

CAS Number

[2070009-45-7]

Target

Mitochondrial Metabolism; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C(O[Na])[C@]1([C@H](CC(NC)=O)C2=O)C(N2CC(C=C3)=CC=C3C4=CC=CC=C4)=CCCC1

Molecular Formula

C25H25N2NaO4

Molecular Weight

440.47

References & Citations

[1]Takeuchi T et al. Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity. J Am Chem Soc. 2015 Jan 21;137 (2) :564-7.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Curated Selection

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