Hippuryl-His-Leu-OH
Product Specifications
UNSPSC Description
Hippuryl-His-Leu-OH is a substrate for detecting the activity of angiotensin I converting enzyme. The His-Leu released by Hippuryl-His-Leu-OH can react with o-phtbaldialdehyde or Fluorescamine (HY-D0715) for fluorescence detection[1][2][3].
Target Antigen
Amino Acid Derivatives; Angiotensin-converting Enzyme (ACE)
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease;Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hippuryl-his-leu-oh.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@@H](NC(CNC(C1=CC=CC=C1)=O)=O)CC2=CN=CN2)=O
Molecular Weight
429.47
References & Citations
[1]Nishimura K, et al. Purification of angiotensin I-converting enzyme from human lung. Biochim Biophys Acta. 1977 Aug 11;483(2):398-408. |[2]Santos RA, et al. An improved fluorometric assay of rat serum and plasma converting enzyme. Hypertension. 1985 Mar-Apr;7(2):244-52.|[3]Horiuchi M, et al. Method for determination of angiotensin-converting enzyme activity in blood and tissue by high-performance liquid chromatography. J Chromatogr. 1982 Dec 10;233:123-30.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P4551/Hippuryl-His-Leu-OH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P4551/
Clinical Information
No Development Reported
CAS Number
31373-65-6
Curated Selection
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