CMP98
CMP98, a PROTAC, is unable to induce degradation of VHL. CMP98 can be used as a negative control compound for CM11[1]. CMP98 consists of two von Hippel-Lindau ligands on their active domain.
Product Specifications
CAS Number
[2244684-50-0]
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cmp98.html
Purity
99.72
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
O=C(N(C[C@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H]4O)[C@@H](C4)C(NCC5=CC=C(C(SC=N6)=C6C)C=C5)=O)=O)=O)=O
Molecular Formula
C58H82N8O14S2
Molecular Weight
1179.45
References & Citations
[1]Alessio CIULLI, et al.Small molecules. WO2018189554A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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