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CMP98

CMP98, a PROTAC, is unable to induce degradation of VHL. CMP98 can be used as a negative control compound for CM11[1]. CMP98 consists of two von Hippel-Lindau ligands on their active domain.

Product Specifications

CAS Number

2244684-50-0

UNSPSC

12352005

Target

PROTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cmp98.html

Purity

99.72

Solubility

DMSO : 120 mg/mL (ultrasonic)

Smiles

O=C(N(C[C@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H]4O)[C@@H](C4)C(NCC5=CC=C(C(SC=N6)=C6C)C=C5)=O)=O)=O)=O

Molecular Formula

C58H82N8O14S2

Molecular Weight

1179.45

References & Citations

[1]Alessio CIULLI, et al.Small molecules. WO2018189554A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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