A375 SMAD/TGFbeta Reporter (Luc) stable cell line

A375 SMAD/TGFbeta Reporter (Luc) cells are derived from the human melanoma A375 cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. A375 cell line has been widely used in cancer research and drug development. A375 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.